Q. Explain the CRISPR-Cas9 gene-editing technology. Discuss, in Indian context, the benefits and challenges associated with genomics revolution. (250 words)
Model Answer : Approach: Why in news? Gene-editing and CRISPR-Cas9 Benefits associated with genomics revolution Challenges associated with genomics revolution Conclusion Why in news? Recently, three studies related to CRISPR-Cas9 gene-editing were published in the scientific journal, Nature Medicine. US scientists have successfully edited the DNA of human embryos to erase a heritable heart condition that is known for causing sudden death. In May 2017, it was shown that in mice it is possible to shut down HIV-1 replication and even eliminate the virus from infected cells. Researchers from the Oregon Health and Science University in California, China and South Korea repaired a mutation in human embryos by using a gene-editing tool called CRISPR-Cas9. Clinical trials are under way in China and in the US to use this tool for treating cancer. In agriculture, a new breed of crops that are gene-edited will become commercially available in a few years. Gene-editing an